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KALAMAZOO, Mich. — The first shipments of a COVID-19 vaccine for widespread use in the United States headed Dec. 13 from Michigan to distribution centers across the country, with the first shots expected to be given in the coming week to health care workers and at nursing homes.

FedEx Corp. has agreed to acquire ShopRunner, an e-commerce service that provides shipping for more than 100 brands, as the courier seeks to deepen its ties with online shoppers.

While it remains to be seen how the pandemic might shift air freight patterns over the long term, this listing of the 100 busiest cargo airports in North America provides an overview of the most important hubs for air freight.

FedEx Corp. and UPS Inc. are girding for their biggest test yet in the e-commerce era, with “Christmas Creep” pushing the holiday shopping season ever earlier and stretching the limits of shipping networks already strained by the COVID-19 pandemic.

Dell Technologies Inc., FedEx Corp. and Switch Inc. are building a U.S. network of data centers, offering businesses an alternative to maintaining their own server farms or using major cloud providers such as Amazon .com Inc. and Microsoft Corp.

FedEx Corp. is pledging to avoid transportation logjams when a massive operation begins to deliver a coronavirus vaccine.

Three members of the trucking industry who demonstrated courage and selflessness during the early days of the coronavirus pandemic were honored by Transport Topics during American Trucking Associations’ Management Conference & Exhibition. See the video.

FedEx Corp. is looking at using small self-flying cargo planes to serve remote areas after experimenting with a technology startup on autonomous aircraft, CEO Fred Smith said.

A huge surge in e-commerce deliveries to homes and businesses because of the COVID-19 pandemic boosted FedEx Corp.’s fiscal first-quarter earnings when the delivery giant reported its financials Sept. 15.

FedEx Corp. is positioning itself for what it is predicting will be an unprecedented peak holiday shipping season, the company said Sept. 8.